Key takeaways
Expert AI answers from UpToDate’s own content: 13,000+ topics maintained by about 7,600 physician authors, editors and peer reviewers, according to Wolters Kluwer.
Personal access comes with UpToDate Pro Plus (US and Canada) or a trainee subscription; institutional access comes through UpToDate Enterprise Edition.
Wolters Kluwer added AI drug dosing guidance for US clinicians in August 2026 and reports pilots at 230+ sites in 36 countries.
Main limitation: answers draw on UpToDate rather than the wider literature, which makes them easier to trace but narrower than a literature search, and no single price is published.
Side-by-side comparison
| Criterion | UpToDate Expert AI | OpenEvidence | Vera Health |
|---|---|---|---|
| Evidence base | UpToDate’s expert-written topics and drug content (13,000+ topics, per Wolters Kluwer). | Licensed journals including NEJM and JAMA, plus FDA and CDC sources (35 million+ papers, vendor figure). | 60 million+ papers, guidelines and care pathways (vendor figure). |
| Who can use it | Pro Plus or trainee subscribers in the US and Canada, and Enterprise Edition accounts; availability varies by region. | Verified US clinicians; its terms exclude the EU, EEA and UK. | Licensed clinicians and trainees; Vera says it can be used outside the US except in sanctioned countries. |
| Cost | Paid; the price depends on role, country and package. | Free for verified US clinicians; ad-supported. | Free for licensed clinicians and trainees; enterprise pricing is custom. |
| Drug and dosing help | AI drug dosing guidance with stated assumptions for US clinicians (added August 2026); Pro Plus adds kidney dosing and antidepressant switching tools. | No drug dosing tools in our review. | Drug database with dosing, interaction checks and 900+ calculators. |
| Where you use it | UpToDate web and apps, a separate Expert AI mobile app, EHR links, and partner products such as Suki’s Ask. | Web and iOS and Android apps, with Visits documentation and a patient Dialer. | Web and iOS and Android apps. |
Based on Wolters Kluwer’s Expert AI, Pro Plus and news pages (checked October 20, 2026), OpenEvidence’s App Store listing and terms, and Vera Health’s App Store listing and terms. Vendor figures are labeled as such.
Which tool fits which situation
Best if your organization already licenses UpToDate
UpToDate Expert AI
Answers stay inside expert-written UpToDate content with graded recommendations, and Enterprise Edition adds usage analytics and governance. Check whether your account already includes Expert AI before paying for an upgrade.
Our #1 ranked tool
Vera Health
Free for licensed clinicians and trainees, with cited answers, drug interaction checks and 900+ calculators, and access outside the US. Its accuracy figures are vendor-run, so test it on your own questions.
Free cited answers in the US
OpenEvidence
Cited answers from licensed journals at no cost to verified US clinicians, plus Visits documentation and a Dialer. Not available in the EU, EEA or UK.
UpToDate answers inside Doximity
Doximity Ask
Doximity and Wolters Kluwer announced on October 20, 2026 that clinicians at health systems using both will see UpToDate answers alongside Doximity Ask’s own answer in the coming weeks.
What is UpToDate Expert AI?
UpToDate Expert AI is a generative AI interface to UpToDate, the clinical reference from Wolters Kluwer. Clinicians ask questions in plain language and get answers built from UpToDate’s topics and drug content, linked to the underlying topics. Wolters Kluwer describes it as support for evaluation, diagnosis, drug dosing and treatment. Main limitation: it summarizes what UpToDate’s editors have reviewed rather than every new study, so it complements rather than replaces a literature search.
Is UpToDate Expert AI free?
No. Expert AI comes with paid UpToDate access. For individuals, Wolters Kluwer offers it in the UpToDate Pro Plus package for professional subscribers in the US and Canada, and at lower rates in trainee subscriptions where available. Prices depend on your country, role and package, and the UpToDate store shows them only after you choose those details. Many clinicians already have access through an employer: about 2,500 US hospitals and health systems use it through UpToDate Enterprise Edition, according to Wolters Kluwer.
How do you get access to UpToDate Expert AI?
Start with the access you may already have, then choose a package only if you need one.
- •Check your institution first: Wolters Kluwer says more than 90% of its US Enterprise Edition customers have adopted Expert AI.
- •As an individual in the US or Canada, choose the Pro Plus package; it also adds state CME tracking, offline topic access through MobileComplete, and kidney dosing and antidepressant switching tools.
- •Trainees can get Expert AI through a trainee subscription where it is offered; the trainee store page says these subscriptions do not accrue CME credit.
- •Outside the US and Canada, availability varies by region; Wolters Kluwer reports pilots at 230+ sites in 36 countries.
- •On mobile, use the UpToDate app or the separate Expert AI app for iOS and Android.
What changed in 2026?
Wolters Kluwer has extended Expert AI from a feature inside UpToDate to a service other clinical products can call.
- •August 2026: AI drug dosing guidance for US clinicians, with stated assumptions and a supporting rationale.
- •October 8, 2026: Suki launched Ask in its clinician app, the first product built on the UpToDate Expert AI API.
- •October 20, 2026: Doximity and Wolters Kluwer announced that UpToDate answers will appear in Doximity Ask for health systems that use both.
UpToDate Expert AI vs OpenEvidence
Both answer clinical questions with citations, but they draw on different sources and charge differently. Expert AI stays within UpToDate’s expert-written, graded content and is paid; OpenEvidence draws on licensed journal content and is free for verified US clinicians, funded by advertising. Choose Expert AI when your organization standardizes on UpToDate and wants AI answers that match its reference content; choose OpenEvidence for free literature-based answers in the US. Main limitation for both: their accuracy claims come largely from the vendors, so test them on questions from your own practice.
When is Vera Health a better choice?
If you pay for your own tools or practice outside the US and Canada, Vera Health covers much of the same ground at no cost: cited answers from 60 million+ papers and guidelines, a drug database with interaction checks, and 900+ calculators, free for licensed clinicians and trainees. It is the top-ranked tool in our 2026 evaluation. Main limitation: Vera has no equivalent of UpToDate’s expert-written topic library and graded recommendations, and its paper and calculator counts are vendor figures.