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Glossary

Clinical AI Glossary

Key terms in clinical decision support AI — clear, evidence-grounded definitions written for physicians and healthcare professionals.

Clinical Decision Support (CDS)

Clinical decision support (CDS) refers to health information technology systems that provide clinicians with knowledge, patient-specific data, and intelligently filtered information at the point of care to improve clinical decisions.

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AI Clinical Decision Support

AI clinical decision support refers to clinical decision support systems that use artificial intelligence — including large language models, machine learning, and natural language processing — to analyze patient data and generate evidence-based clinical recommendations.

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Prompt Injection in Medical AI

Prompt injection is a security vulnerability in AI systems where malicious or misleading input causes the model to ignore its intended instructions and generate unintended, potentially harmful output. In medical AI, this risk is particularly serious because it could lead to incorrect clinical recommendations.

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Evidence-Based AI

Evidence-based AI refers to artificial intelligence systems that ground their outputs in verifiable, peer-reviewed evidence rather than relying solely on pattern-learned associations. In clinical contexts, this means every AI-generated recommendation is linked to its original source in the medical literature.

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Medical LLM

A medical LLM (large language model) is an AI model trained or fine-tuned specifically for medical and clinical applications. Medical LLMs are designed to understand clinical terminology, reason about patient presentations, and generate evidence-informed medical text.

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DoxGPT

DoxGPT is Doximity's AI-powered clinical assistant built into the Doximity platform. It provides drug information, clinical summaries, and documentation assistance to physicians as part of Doximity's broader professional network for healthcare providers.

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OpenEvidence

OpenEvidence is an AI-powered medical information platform for healthcare professionals that provides cited, evidence-based answers to clinical questions. Founded by Harvard researchers and launched via Mayo Clinic Platform Accelerate, it partners with NEJM and JAMA Network for content.

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AI Hallucination in Healthcare

AI hallucination in healthcare occurs when an artificial intelligence model generates medical information that is factually incorrect, fabricated, or not grounded in any real evidence — yet presents it with high confidence. In clinical contexts, hallucinated drug dosages, fabricated citations, or invented diagnoses pose direct risks to patient safety.

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Ambient AI Scribe

An ambient AI scribe is a clinical documentation tool that uses automatic speech recognition and natural language processing to listen to patient-physician conversations in real time and automatically generate structured clinical notes for the electronic health record.

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SMART on FHIR

SMART on FHIR (Substitutable Medical Applications, Reusable Technologies on Fast Healthcare Interoperability Resources) is an open standard that enables third-party healthcare applications — including clinical AI tools — to securely connect to electronic health record systems and exchange patient data.

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Retrieval-Augmented Generation (RAG)

Retrieval-augmented generation (RAG) is an AI architecture that enhances large language models by retrieving relevant information from external knowledge sources before generating a response. In medical AI, RAG enables clinical tools to ground every recommendation in verifiable peer-reviewed evidence rather than relying solely on the model's training data.

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AI Differential Diagnosis

AI differential diagnosis refers to the use of artificial intelligence to generate a ranked list of possible diagnoses from a patient's clinical presentation — including symptoms, lab values, imaging findings, and medical history. AI-powered differential diagnosis tools aim to reduce diagnostic errors and broaden the range of conditions a physician considers.

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Generative AI in Healthcare

Generative AI in healthcare refers to artificial intelligence systems — primarily large language models — that can produce new content such as clinical text, diagnostic assessments, treatment summaries, and patient communications based on medical knowledge and patient data.

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EHR Integration for Clinical AI

EHR integration for clinical AI refers to the ability of AI-powered clinical tools to connect directly with electronic health record systems — enabling AI to access patient data, deliver recommendations within the clinician's existing workflow, and reduce the friction of switching between applications.

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AI Clinical Validation

AI clinical validation is the process of testing an artificial intelligence medical tool against real-world clinical scenarios, established benchmarks, and peer-reviewed evidence to demonstrate that it produces accurate, safe, and clinically useful output for healthcare professionals.

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Natural Language Processing (NLP) in Medicine

Natural language processing (NLP) in medicine is the branch of artificial intelligence that enables computers to understand, interpret, and generate human language in clinical contexts — powering applications from clinical documentation to medical literature search to conversational clinical decision support.

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AI Drug Interaction Checker

An AI drug interaction checker is a clinical tool that uses artificial intelligence to identify potential harmful interactions between medications, supplements, and patient conditions — going beyond traditional database lookups by analyzing complex multi-drug regimens, patient-specific factors, and emerging evidence from the medical literature.

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Clinical AI Governance

Clinical AI governance is the organizational framework of policies, oversight structures, and processes that healthcare institutions use to evaluate, deploy, monitor, and maintain AI tools in clinical practice — ensuring safety, accuracy, equity, and regulatory compliance.

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AI-Powered Risk Stratification

AI-powered risk stratification uses artificial intelligence to analyze patient data and assign risk scores that predict the likelihood of clinical outcomes — such as hospital readmission, disease progression, adverse events, or treatment response — enabling physicians to prioritize interventions for higher-risk patients.

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CDSS vs AI Clinical Decision Support

Traditional clinical decision support systems (CDSS) use rule-based logic and curated knowledge bases to generate alerts and recommendations, while AI-powered clinical decision support uses machine learning, large language models, and natural language processing to reason across evidence and generate more flexible, context-aware clinical guidance.

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