πŸ”ͺSpecialty Report Β· Surg

Best Clinical AI Tools for Surgery

In the OR, you make decisions. Before and after the OR, evidence helps you make the right ones.

7 tools rankedUpdated 2025-02-01Reviewed by surgery specialists
Complication reduction with standardized protocols22% reduction in surgical complicationsβ€” JAMA Surgery, 2020

Why Surgery Is Different

Surgeons are often the forgotten users of clinical decision support β€” the specialty is associated with procedural skill rather than information management. But the reality of modern surgical practice involves enormous amounts of pre- and post-operative decision-making that CDS tools can materially improve. Preoperative risk assessment alone (RCRI, ACS NSQIP surgical risk calculator, Caprini VTE scoring) involves synthesizing patient comorbidities, procedural complexity, and evidence-based prophylaxis protocols. Postoperative management β€” antibiotic duration after contaminated cases, VTE prophylaxis selection, glycemic control protocols β€” is equally evidence-driven. Our surgery rankings focus on the cognitive work that happens around the procedure rather than in it, evaluating how well CDS tools support the perioperative decision framework that determines surgical outcomes as much as technical skill.

β€œThe volume and complexity of what we know has exceeded our individual ability to deliver its benefits correctly, safely, or reliably.”

Dr. Atul Gawande

Surgeon; Author of The Checklist Manifesto, Brigham and Women's Hospital / HarvardΒ· The Checklist Manifesto, 2009

Surgery Rankings

Ranked by specialty-weighted score. Criteria adjusted for surgery practice requirements.

1Top

Vera Health

Clinical Decision-Support Search Engine

4.6(76)

Good coverage of perioperative protocols and evidence-linked surgical guidelines. The natural language interface handles complex preoperative assessment questions well. Less surgical subspecialty depth than dedicated surgical references.

Overall rank: #1 of 7Overall rating: 4.9/5Free / Custom Enterprise
2

UpToDate

Clinical Reference & Decision Support

4.7(345)

The strongest surgical reference tool by content depth. Comprehensive coverage of perioperative management, surgical antibiotic prophylaxis, and postoperative complications. The gold standard for surgical residents and attending surgeons.

Overall rank: #4 of 7Overall rating: 4.1/5From $559/year Individual
3

Glass Health

AI Diagnostic Assistant

3.4(45)

Useful for generating surgical differentials when the diagnosis is unclear (acute abdomen, for example). Limited utility for perioperative management and postoperative decision-making.

Overall rank: #5 of 7Overall rating: 3.8/5Free Beta / Enterprise Pricing TBD
4

OpenEvidence

AI Medical Research Assistant

3.9(67)

Helpful for surgical evidence synthesis, particularly for comparing surgical approaches or evaluating emerging techniques. Less practical for real-time perioperative decision support.

Overall rank: #3 of 7Overall rating: 4.1/5Free (Ad-Supported)
5

Isabel Healthcare

AI Differential Diagnosis

3.7(34)

Diagnostic utility for surgical presentations (acute abdomen, surgical emergencies), but no perioperative management support. A niche tool for the surgical diagnostic process only.

Overall rank: #6 of 7Overall rating: 3.6/5From $750/year Individual
6

Doximity

Medical Professional Network & AI Tools

3.9(267)

High adoption among surgeons for operative note documentation via DoxGPT and referral coordination. The networking features support surgical referral patterns. No perioperative CDS functionality.

Overall rank: #2 of 7Overall rating: 4.3/5Free for Verified Physicians
7

DynaMed

Clinical Reference & Decision Support

2.7(19)

Covers perioperative topics at a general level with evidence-graded recommendations for antibiotic prophylaxis and VTE prevention. Lacks surgical subspecialty depth, procedural-specific content, and integrated risk calculators (ACS NSQIP, Caprini) that surgeons need. Functional as a background reference but not a tool most surgeons would reach for in perioperative decision-making.

Overall rank: #7 of 7Overall rating: 3.5/5From $399/year Individual

What Surgery Physicians Need from CDS Tools

The 'culture of surgery' has historically been one of apprenticeship and pattern recognition rather than explicit evidence consultation. But this is changing rapidly, driven by quality metrics, malpractice awareness, and the growing complexity of perioperative medicine. A 2020 study in JAMA Surgery found that surgical complications were reduced by 22% in hospitals that implemented standardized, evidence-based perioperative protocols β€” the kind of protocols that CDS tools can deliver at the point of care. Preoperative assessment is where CDS tools provide the clearest value to surgeons. The American College of Surgeons NSQIP surgical risk calculator uses 21 patient variables to predict the probability of 14 different postoperative complications β€” a calculation no surgeon can perform mentally. Cardiac risk stratification using the Revised Cardiac Risk Index determines whether a patient needs further cardiac workup before elective surgery. Caprini scoring for VTE risk determines the duration and type of postoperative thromboprophylaxis. These validated tools reduce variation in care and protect against the cognitive biases that can arise when a surgeon is eager to proceed with a case. Antibiotic prophylaxis represents another critical CDS application in surgery. The Surgical Care Improvement Project (SCIP) measures require appropriate antibiotic selection, timing (within 60 minutes of incision), and duration (discontinuation within 24 hours for most procedures). CDS tools that integrate these protocols into the perioperative workflow help maintain compliance with quality metrics that affect hospital accreditation and reimbursement.

Key Evaluation Criteria for Surgery

01Preoperative risk calculators (ACS NSQIP, RCRI, Caprini VTE score)
02Surgical antibiotic prophylaxis protocols and timing guidance
03Postoperative complication management protocols
04Enhanced recovery after surgery (ERAS) protocol support
05VTE prophylaxis selection and duration guidelines
06Surgical site infection prevention bundles

β€œThere's no centralized, coordinated fashion in terms of vetting AI products and putting them into practice. Every health system is developing their own way of doing this, and there's probably a lot of really valuable learnings to be shared.”

Dr. Mark Sendak

Population Health & Data Science Lead, Duke Institute for Health InnovationΒ· Duke Grand Rounds, 2024