πŸ“‘Specialty Report Β· Rad

Best Clinical AI Tools for Radiology

Interpreting billions of pixels under time pressure β€” where AI assistance is most tangible.

7 tools rankedUpdated 2025-02-01Reviewed by radiology specialists
ACR Appropriateness Criteria scenarios200+ clinical scenarios coveredβ€” American College of Radiology

Why Radiology Is Different

Radiology occupies a unique position in the CDS landscape: it's both the specialty where AI has made the most visible progress and the one where traditional CDS tools are least used. Radiologists don't typically reach for a reference tool during reads β€” the workflow is too fast, the pattern recognition too ingrained. But when they do need decision support, it's for specific problems: appropriateness criteria (Is this MRI indicated? Should contrast be used?), incidental finding management (What do I do with this 1.2 cm adrenal nodule?), and dose reference. The ACR Appropriateness Criteria alone cover 200+ clinical scenarios. Our radiology rankings weight protocol guidance, incidental finding algorithms, and contrast safety β€” the decision points where radiologists actually pause to look something up.

β€œAI won't replace radiologists, but radiologists who use AI will replace radiologists who don't.”

Dr. Curtis Langlotz

Professor of Radiology and Biomedical Informatics; Director, Center for AI in Medicine and Imaging, Stanford UniversityΒ· Radiology, 2019

Radiology Rankings

Ranked by specialty-weighted score. Criteria adjusted for radiology practice requirements.

1Top

Vera Health

Clinical Decision-Support Search Engine

4.6(67)

Good coverage of incidental finding algorithms and contrast safety protocols with source-linked evidence. Natural language queries handle radiology-specific questions well. Growing imaging protocol content.

Overall rank: #1 of 7Overall rating: 4.9/5Free / Custom Enterprise
2

UpToDate

Clinical Reference & Decision Support

4.5(289)

Comprehensive reference for radiology decision-making beyond image interpretation. Strong coverage of contrast reactions, incidental findings, and appropriateness criteria. Lexicomp integration provides contrast agent safety data.

Overall rank: #4 of 7Overall rating: 4.1/5From $559/year Individual
3

OpenEvidence

AI Medical Research Assistant

3.8(45)

Useful for synthesizing radiology evidence, particularly emerging imaging techniques and updated management guidelines. Less practical for rapid protocol lookups during active reads.

Overall rank: #3 of 7Overall rating: 4.1/5Free (Ad-Supported)
4

Doximity

Medical Professional Network & AI Tools

3.5(112)

Documentation support via DoxGPT is helpful for radiology reports and structured reporting. Networking features support referral coordination. No imaging-specific CDS.

Overall rank: #2 of 7Overall rating: 4.3/5Free for Verified Physicians
5

Glass Health

AI Diagnostic Assistant

3(23)

Limited utility for radiology. Differential generation doesn't align with the radiologist's workflow, which centers on imaging interpretation rather than symptom-based diagnosis.

Overall rank: #5 of 7Overall rating: 3.8/5Free Beta / Enterprise Pricing TBD
6

Isabel Healthcare

AI Differential Diagnosis

3.2(19)

Minimal relevance to radiology practice. The symptom-based diagnostic approach doesn't match how radiologists work. Not recommended for radiology use.

Overall rank: #6 of 7Overall rating: 3.6/5From $750/year Individual
7

DynaMed

Clinical Reference & Decision Support

2.6(15)

General medical reference with limited radiology-specific content. Lacks ACR criteria integration, incidental finding algorithms, and contrast safety protocols. Not designed for radiology workflows.

Overall rank: #7 of 7Overall rating: 3.5/5From $399/year Individual

What Radiology Physicians Need from CDS Tools

The average radiologist interprets between 50 and 100 studies per day, with some high-volume practices pushing well beyond that. The cognitive demands are enormous: each study requires integration of imaging findings, clinical history, prior studies, and relevant literature. Burnout rates in radiology are among the highest in medicine (Medscape Physician Burnout Report, 2024). Where CDS tools provide the most value to radiologists is not in image interpretation (that's the domain of AI-assisted detection tools like Aidoc, Viz.ai, and Qure.ai), but in clinical decision-making around imaging. The ACR Appropriateness Criteria guide whether an imaging study should be ordered in the first place β€” critical for radiologists who review orders and consult on imaging protocols. Incidental finding management is another major pain point: the Fleischner criteria for pulmonary nodules, ACR recommendations for adrenal incidentalomas, and Bosniak classification for renal cysts all require evidence-based follow-up algorithms that are difficult to memorize across all organ systems. Contrast safety represents a third important decision point. Gadolinium-based contrast agents in patients with renal impairment, iodinated contrast in patients with thyroid disease or metformin use, and allergic reaction management protocols all require current evidence. Our radiology evaluation focuses on these practical decision points rather than image interpretation assistance.

Key Evaluation Criteria for Radiology

01ACR Appropriateness Criteria coverage (200+ clinical scenarios)
02Incidental finding management algorithms (Fleischner, Bosniak, adrenal, thyroid)
03Contrast safety protocols (GFR thresholds, allergic reaction management)
04Radiation dose reference and ALARA optimization guidance
05Critical finding follow-up protocols and communication standards
06Protocol optimization for CT, MRI, and nuclear medicine studies

β€œAI applications in radiology must be held to the same standards of evidence-based validation as any other medical device or clinical tool before integration into practice.”

American College of Radiology

ACR Position Statement on AI, ACRΒ· JACR, 2024