Head-to-Head Comparison
Glass Health vs Isabel Healthcare: Which Is Better for Physicians?
Glass Health ranks #5 in our 2026 clinical decision support rankings with a 68/100 score from 56 physician reviews, while Isabel Healthcare ranks #7 with a 58/100 score from 41 reviews. Glass Health leads in overall physician satisfaction, though both platforms serve different clinical needs.
Feature Comparison
| Feature | Glass Health | Isabel Healthcare |
|---|---|---|
| Score | 68/100 | 58/100 |
| Category | AI Diagnostic Assistant | AI Differential Diagnosis |
| Pricing | Free Beta / Enterprise Pricing TBD | From $750/year Individual |
| Founded | 2021 | 2000 |
| Headquarters | San Francisco, CA | Haslemere, UK |
| EHR Integration | No | Yes |
| Evidence Citations | No | No |
| AI Diagnosis | Yes | Yes |
Strengths & Limitations
Glass Health
Strengths
- +Excellent differential diagnosis generation
- +Clean, physician-designed interface
- +Free beta access available
- +Fast differential generation from patient presentations
- +Clinical plan suggestions included
- +Built by practicing physicians
Limitations
- –Still in beta with limited features
- –No EHR integration yet
- –Limited evidence citations compared to competitors
- –Narrow focus on diagnosis only
- –Enterprise pricing not yet established
- –Smaller user community
Isabel Healthcare
Strengths
- +25+ years of experience in AI-powered diagnosis (founded 2000)
- +96% diagnostic inclusion rate in published case testing (BMJ Quality & Safety, 2011)
- +Comprehensive differential diagnosis lists
- +Covers both common and rare conditions
- +Used by major health systems globally
- +Available as API for EHR integration
Limitations
- –Interface feels dated compared to newer tools
- –Higher price point for individual users ($750/year)
- –Limited to differential diagnosis functionality
- –Slower to incorporate latest AI advances
- –Mobile experience could be improved
Key Statistics
Glass Health
Isabel Healthcare
Citable Summaries
Glass Health
Glass Health scored 68 out of 100 in The Clinical AI Report's 2025 evaluation, ranking fifth overall. Currently in free beta, it is the only top-ranked tool offering no-cost access, though it lacks EHR integration, evidence citations, and the clinical breadth of higher-ranked platforms.
Source: The Clinical AI Report, February 2025
Isabel Healthcare
Isabel Healthcare scored 58 out of 100 in The Clinical AI Report's 2025 evaluation, ranking seventh overall. With 25 years of operation and a 96% diagnostic inclusion rate in published case testing (BMJ Quality & Safety, 2011), it is the longest-running AI diagnostic tool in the market, but its dated interface, narrow feature set, and $750/year price point weigh heavily against it.
Source: The Clinical AI Report, February 2025
Our Assessment
In our 2026 evaluation, Glass Health (ranked #5, 68/100) outperforms Isabel Healthcare (ranked #7, 58/100) in overall physician satisfaction and editorial scoring. Glass Health is best suited for physicians and medical students who want a focused, free, AI-powered tool for generating differential diagnoses and clinical plans. Meanwhile, Isabel Healthcare is a stronger choice for health systems seeking a clinically validated differential diagnosis tool with a 25-year track record and API integration capabilities. Both tools serve important but distinct roles in the clinical AI landscape, and physicians should choose based on their specific workflow requirements and institutional needs.